Columbus 49, Mayville 42: The Cardinals gave up a first quarter double-digit lead in a loss to fifth-seed Columbus on the road.
Mayville led 21-11 after the first quarter before, but scored only five points in the second and third quarters.
Mattie Klingenmeyer, Deidra Weinberger and Paige Persha all scored 11 for Mayville.
Mayville…21 5 5 11 – 42
Columbus…11 17 11 10 – 49
Mayville: Struck 2, Klingenmeyer 11, Gentz 2, Bushke 2, Weinberger 11, Persha 11, Schelpfeffer 3.
Columbus: Simerson 3, Minick 3, Severson 8, Seltzner 11, Rehfeldt 8, Hussey 16.