Davenport Central (1-3) at West High (0-4)
Where: Trojan Field, 7:15 p.m.
Last season: West High 28, Davenport Central 24
Keep an eye on: Davenport Central junior running back Koby Williams (5-6, 180) is averaging 9.0 yards per carry this season while rushing for 251 yards and two touchdowns.
Key stat: Davenport Central opponents are completing 63 percent of their passes this season with eight touchdowns and one interception.
What to watch: West High’s high-powered pass offense faces a Blue Devil defense that has allowed its last two opponents to complete 62 percent of its passes for 506 yards and six touchdowns.
About West High: The Trojans failed to convert a pair of two-point conversions in a 14-12 loss to crosstown rival City High on Friday while falling to 0-4. After scoring 31 points in its opener, West High has scored 25 points in its last three games.
About Davenport Central: After a season-opening win over Burlington, the Blue Devils have dropped three games by a combined score of 108-34. Davenport Central’s current three-game losing skid has come against teams with a combined 11-1 record.
Ottumwa (3-1) at City High (2-2)
Where: Bates Field, 7:15 p.m.
Last season: Ottumwa 34, City High 0
Keep an eye on: Ottumwa senior running back Isaiah Cox (5-11, 200) has rushed for 2,188 yards and 20 touchdowns over the past three seasons.
Key stat: Ottumwa held City High to 58 rushing yards in a 34-0 win last season.
What to watch: Over the last three seasons, City High and Ottumwa have both played seven games decided by less than eight points. City High is 6-1 in those games, Ottumwa is 3-4.
About City High: Following back-to-back losses to ranked teams to start the year, City High has won two straight after Friday’s 14-12 win over City High. The Little Hawks allowed 79 points in losses to Cedar Falls and Bettendorf, but have allowed a combined 22 points during its two-game winning streak.
About Ottumwa: The Bulldogs had a three-game winning streak snapped with a 21-13 loss to 10th-ranked Indianola last week. Ottumwa outgained City High 397-222 in a 34-0 win over the Little Hawks last season.
Clear Creek Amana (1-3) at Keokuk (1-3)
Where: Calvert Stadium in Keokuk, 7:30, p.m.
Last season: Clear Creek Amana 52, Keokuk 7
Keep an eye on: Keokuk senior wide receiver Colton Marlin (6-2, 185) caught 34 passes for 772 yards last season and had five grabs for 125 yards in the first three games this season.
Key stat: Keokuk is allowing 252.5 rushing yards per game.
What to watch: Clear Creek Amana rushed for 318 yards and six touchdowns in last year’s 52-7 win over Keokuk.
About Keokuk: The Chiefs snapped a three-game losing streak with a 21-14 road win at Mount Pleasant in Week 3 before losing to Davenport Assumption 41-0 last week. Keokuk has been outscored 117-35 on the season.
About Clear Creek Amana: The Clippers erased a five-game losing skid that dated back to last season with a 27-14 win over Fort Madison last week. Clear Creek Amana’s three losses have come to teams with a combined 10-2 record.
Solon (2-2) at Washington (3-1)
Where: Case Field in Washington, 7:15 p.m.
Last season: Solon 28, Washington 17
Keep an eye on: Washington sophomore Ryan Reighard is a dual-threat quarterback for the Demons passing for 479 yards and four touchdowns while running for 453 yards and eight scores.
Key stat: Washington is 11-1 over the past two seasons when scoring 24 points or more. Solon has allowed more than 24 points four times in its last 15 games.
What to watch: Washington has allowed opponents to complete just 3-of-27 passes for 18 yards with two interceptions and no touchdowns in its last two games.
About Solon: The Spartans forced seven turnovers in a 35-0 shutout of Marion last week. Solon has held opponents to an average of 149 yards per game in its two wins and allowed 322.5 yards per game in two losses.
About Washington: The Demons have won three straight since a season-opening loss to top-ranked Pella and then downing Fairfield 23-0 on Friday. Washington is averaging 31 points and 372 yards of offense during its current three-game winning streak and holding opponents to 137 yards and 6.3 points.
Class 1A No. 1 Regina (4-0) at Highland (3-1)
Where: Highland High School, 7 p.m.
Last season: Regina 49, Highland 14
Keep an eye on: Regina senior quarterback Nathan Stenger has completed 64 percent of his passes (32-50) for 438 yards and seven touchdowns with an interception in his last three games. He has also run for 139 yards and four more scores.
Key stat: The Regina defense has forced 18 turnovers in four games.
What to watch: Regina has averaged 7.8 yards per offensive play in its last three games.
About Regina: The top-ranked Regals have flexed their muscles in their last three wins averaging 57.3 points and 438 total yards while outscoring opponents 172-36. Senior Nick Phillips has rushed for 408 yards with six touchdowns and has 12 receptions for 188 yards and three scores.
About Highland: The Huskies bounced back from a loss to Columbus with a 14-6 road win over West Marshall last week. Junior quarterback Jake Wood had passed for 499 yards and seven touchdowns for Highland and has run for 160 yards and two more scores.
Class 2A No. 8 Mid-Prairie (4-0) at Sigourney/Keota (2-2)
Where: Sigourney, 7:30 p.m.
Last season: Mid-Prairie 38, Sigourney/Keota 20
Keep an eye on: Sigourney/Keota senior Peyton Crawford is coming of a 357-yard, six-touchdown performance and has rushed for 704 yards and nine touchdowns this season.
Key stat: Sigourney/Keota is 7-7 over the past two seasons. Crawford has rushed for 1,761 yards and 25 touchdowns in the seven wins and 651 yards and six scores in the seven losses.
What to watch: Mid-Prairie is yielding just 115 rushing yards per game and 3.1 yards per carry this season and will get a test from Crawford, who has rushed for 1,705 yards with 26 touchdowns. He averages 10.5 yards per carry in his last eight games dating back to last season.
About Mid-Prairie: The Golden Hawks posted back-to-back shutouts for the first time since 2012 with a 27-0 shutout of West Burlington/Notre Dame on Friday. Mid-Prairie is doing it with its potent running game and a smothering defense. The Golden Hawks are averaging 259.5 rushing yards per game while holding foes to 206 yards of total offense.
About Sigourney/Keota: The Savage Cobras bounced back from a 52-6 loss to Regina in Week 3 with a 52-35 win over Pella Christian last week. Sigourney/Keota’s two losses have come to a pair of top-ranked teams in 1A No. 1 Regina and Class A top-ranked BGM in Week 1. Sigourney/Keota is 6-0 the past two seasons when Crawford runs for more than 161 yards.
West Liberty (0-4) at Mediapolis (2-2)
Where: Archer Field in Mediapolis, 7:30 p.m.
Last season: Mediapolis 40, West Liberty 13
Keep an eye on: Mediapolis senior quarterback Arthur Brown (5-10, 150) has passed for 690 yards and six touchdowns and has rushed for a team-high 241 yards and three scores.
Key stat: Mediapolis is giving up an average of 124 rushing yards in its two wins this season and has surrendered an average of 369.5 in its two losses.
What to watch: West Liberty held Monticello to 72 yards of total offense in last week’s 14-0 loss.
About West Liberty: The Comets dropped to 0-4 with a 14-0 loss to Monticello last week and have now lost 16 straight dating back to 2013. West Liberty has been challenged early facing four teams with a combined record of 14-2.
About Mediapolis: After opening the season 2-0, Mediapolis has dropped back-to-back road games to District 6 favorites Williamsburg and Central Lee by a combined score of 73-27. Mediapolis allowed an average of 259.5 total yards in its two wins and has given up 503.5 total yards in its two losses.
Class 1A No. 3 West Branch (4-0) at Bellevue (1-3)
Where: C.C. Hammann Field in Bellevue, 7 p.m.
Last season: West Branch 37, Bellevue 7
Keep an eye on: Bellevue sophomore quarterback Cade Daugherty has passed for 476 yards and three touchdowns and leads the Comets with three interceptions from his defensive back spot.
Key Stat: West Branch has scored at least 31 points in 14 of its last 15 games.
What to watch: Bellevue junior Peter Kilburg has accounted for 44 percent of the Comets’ total offense (328 rushing yards, 131 receiving yards).
About Bellevue: The Comets have lost three straight since a win over Easton Valley in the season opener after falling 19-6 to Alburnett in the District 5 opener for both teams. After gaining 337 yards and scoring 13 points in its season-opening win, Bellevue has averaged just 234 yards per game and managed just 20 points during its three-game losing skid.
About West Branch: The Bears improved to 4-0 with a 31-8 win over North Cedar in its district opener last week. Junior running back Luke Lenoch has rushed for 622 yards and eight touchdowns for West Branch, which is averaging 38 points per game.
Lone Tree (3-1) at Class A No. 7 Winfield-Mount Union (4-0)
Where: Winfield, 7 p.m.
Last season: Lone Tree 42, Winfield-Mount Union 30
Keep an eye on: Winfield-Mount Union senior punter Sam Jennings (6-3, 230) was a third-team all-state pick as a punter last season and is averaging 44.3 yards per kick this season. He also leads the Wolves with 36 tackles, including 31 solo stops.
Key stat: Winfield-Mount Union senior running back Darren Hunter (6-0, 205) is averaging 9.6 yards per carry.
What to watch: Lone Tree’s high-octane running game that averages 314.5 yards per game and 7.4 yards per carry that has rushed for 19 touchdowns faces a Winfield-Mount Union defense that is allowing 82 yards per game on the ground on 2.9 yards per carry and has allowed a rushing touchdown.
About Lone Tree: Lone Tree rushed for more than 400 yards for the second consecutive week, rolling up 409 yards on the ground in a 48-6 win over Cardinal. Senior Jared Hudson has rushed for 470 yards and five touchdowns in the past two games and had 240 yards and three scores in a win over Winfield-Mount Union last season.
About Winfield-Mount Union: Through four weeks, Winfield-Mount Union has been one of the most impressive teams in Class A by outscoring opponents 180-6 and outgaining foes by an average of 366-124. The Wolves defeated Danville 44-0 on Friday, their second straight 44-0 win.